COMET, TUNEL, and TEM analysis of an infertile male with short tail sperm

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P-133: Investigation of Genetic Variations in Exon 6 of AKAP4 Gene in Infertile Men with Immotile Short Tail Sperm

Background The immotile short tail sperm (ISTS) defect is one of the disorders that cause male infertility. Men with this condition have immotile short-tail sperm with structural defects in the fibrous sheath(FS). A Kinase Anchoring Protein 4 (AKAP4) is one of the most abundant proteins in the fibrous sheathof sperm flagella and provides scaffold for the correct assembly of FS.Since exon 6 of A...

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Background One of the main causes of male infertility is defect in structure and function of sperm cells. Infertile men with oligoasthenoteratospermia (OAT) defect, have sperms with abnormalities in count, motility and morphology. Patients with immotile short tail sperm (ISTS) disorder have immotile short-tailed sperm with disorganized axonem, and a significant decrease in sperm counts. Numerou...

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Blasting Off on an Actin Comet Tail

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ژورنال

عنوان ژورنال: Journal of the Turkish German Gynecological Association

سال: 2015

ISSN: 1309-0399,1309-0380

DOI: 10.5152/jtgga.2014.0017